Author: Rose Miyatsu
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UCSC Genome Browser alumni profile: Melissa Cline
Melissa Cline is a prominent figure in the field of cancer genomics and currently manages the BRCA Exchange, the largest public resource for knowledge on genetic variations that influence heritable breast, ovarian, prostate, and pancreatic cancers.
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Ancient DNA research aids de-extinction efforts and reveals surprising dire wolf ancestry
UC Santa Cruz scientists worked with Colossal Biosciences to help reveal secrets in the dire wolf genome that contributed to what the startup is calling the world’s first de-extinction
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Clinical pediatric cancer lab at UC Santa Cruz is cleared to accept and test patient samples
The UC Santa Cruz Colligan Clinical Diagnostic Laboratory has received its CLIA certificate of registration from the California Department of Public Health, which clears the way for it to begin accepting patient samples.
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Newest Genome Browser features highlight the power of generative AI and machine learning for biology
The UCSC Genome Browser has added two new datasets that leverage the power of generative AI and machine learning to interpret information about genetic variants and more rapidly assess which ones might be harmful to human health
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25 years of the UCSC Genome Browser
July 2025 will mark the 25th anniversary of the UC Santa Cruz Genome Browser, one of the most widely used resources for genomics worldwide. In celebration of this amazing resource, we are spotlighting alumni who worked on the Browser over the course of its history.
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Powerful new analyses improve breast cancer risk assessment on a massive scale
A new feature on the BRCA Exchange, a platform which consolidates data on the genes associated with breast cancer, is rolling out a new feature to make cancer risk much easier to assess.
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New study discovers cellular activity that hints recycling is in our DNA
Introns are perhaps one of our genome’s biggest mysteries. They are DNA sequences that interrupt the sensible protein-coding information in your genes, and need to be “spliced out.”
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New eDNA Explorer provides a powerful new resource for conservation
CALeDNA has launched a prototype of their new eDNA Explorer, an open-source tool that provides a powerful and easily accessible platform for sharing, exploring, and analyzing data from projects that use environmental DNA.
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Working to improve clarity for patients assessing their genetic breast cancer risk
A project to expedite the analysis of variants on the BRCA 1 and 2 genes, the most commonly affected genes in breast cancer cases, will help more people to better understand their cancer risk.
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Biotech founder and hero of the Human Genome Project joins UC Santa Cruz Genomics Institute as Executive Director
The UC Santa Cruz Genomics Institute has selected scientist, entrepreneur, and executive Lauren Linton as their new Executive Director.
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GREAT program creates new opportunities for students to participate in research
This summer, the “Genome Research Experiences to Attract Talented Undergraduates into the Genomics Field to Enhance Diversity” (GREAT) programmed welcomed six students from California State University Monterey Bay (CSUMB) to an intensive eight-week research program at UC Santa Cruz.
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10 mysteries of the Y chromosome
Researchers have just completed the first full sequence of a Y chromosome — what will we learn?